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") skip to main content toggle navigation login home stroke information isgc publications participants isgc projects links welcome to the international stroke genetics consortium the international stroke genetics consortium (isgc) was organized in april 2007, at the annual meeting of the american academy of neurology in boston. a group of 16 investigators from europe and north america traveled to the broad institute in cambridge, ma for a daylong organizational meeting. the first isgc international workshop was then held in london, july 2007. since then the isgc has held its international workshop every six months. isgc membership and academic impact membership is open to any investigator with the resources to contribute to advancing the mission of the consortium, which is to discover the role of genetic variation in the pathogenesis of cerebrovascular disease and to exploit this new knowledge to reduce the burden of disease worldwide. currently there are 50 member centers. members include stroke neurologists, geneticists, statisticians, fellows, and students. since its founding, the isgc has focused its efforts on 1) performing collaborative studies of genetic risk factors for stroke in well-phenotyped samples, 2) measuring the reliability of phenotyping across centers and 3) securing funding for genome-wide genotyping of stroke samples. accomplishments have included the securing of major research grants from the wellcome trust in the uk, the us national institutes of health, and the australian national research council among others. major publications of the consortium can be found here isgc committees and working groups the isgc steering committee holds conference calls every two months and consists of the chair, vice- chair, past-chair and seven additional committee members. the chair and vice chair hold terms for two years and are internally selected from among steering committee members. committee members are elected by an isgc-wide vote. during the meeting, isgc project proposals are reviewed and updated, future goals and developments are discussed and general action items are addressed. the isgc scientific committee holds conference calls every two months, on an alternating schedule to the steering committee, and consists of two co-chairs and six committee members. during the meetings, the bi-annual isgc workshop is planned. specifically, the dates, meeting location and agenda are planned as well as the themes and focus of each workshop. the isgc analysis working group holds conference calls once a month and consists of two co-chairs and five additional call members. this group was formed to facilitate regular contact amongst the analytical members of the isgc in-between workshops and is an opportunity to exchange ideas, discuss updates as well as coordinate isgc-wide analysis initiatives. among the goals of this committee are to increase efficiency of analyses and create an expert community to aid in solving problems faced by less experienced isgc members. the isgc imaging working group holds conference calls once a month and consists of a chair and vice- chair and nine additional call members. formed in the fall of 2012, this group is undertaking a harmonization of image characterization/measurement approaches across isgc centers and is contributing images to the isgc-ninds stroke imaging repository housed at mgh under dr. rosand’s leadership . the isgc outcomes working group holds conference calls once a month and consists of two co-chairs and seven additional members. formed in the fall of 2012, this group is responsible for harmonizing stroke outcome measures across member sites. the isgc outreach working group holds conference calls once a month and consists of a chair and vice-chair and two additional members. this working group is devoted to expanding isgc participation to underrepresented regions and populations . the translation research working group holds conference calls once a month and consists of a chair and vice-chair and 23 additional members. this group was formed in 2013 with the goal of uniting researchers whose goal is to use genetic and genomic tools to improve understanding of the pathophysiologic basis of cerebrovascular disease. isgc semi-annual international workshop twice a year, the isgc holds a two-day workshop at the home institution of an isgc member. tradition holds that the workshop location rotates among continents. the most recent hosts have been ynte ruigrok in utrecht, netherlands and myriam fornage in houston, texas, usa. each conference program provides updates of ongoing isgc scientific activities, symposia on future projects, scientific sessions, training sessions, and brainstorming sessions. additionally, 2-3 plenary sessions are organized around invited, external speakers to provide expert opinions on topics related to the isgc goals. on average 70 members of the isgc attend each workshop. isgc resources the metastroke collaboration holds conference calls once a month and consists of a chair and vice-chair along with 20 cohort representatives. this group was formed in 2010 to bring together individual studies with large-scale genome-wide association study data to perform meta-analyses to identify new genetic loci for ischemic stroke. the metastroke database currently contains summary statistics for 15,671 cases of ischemic stroke, 9,728 of which do not overlap with ninds-sign, and an excess of controls. the ninds-stroke genetics network (sign) holds conference calls once a month and is governed by a steering committee comprised of all contributing investigators. formed in 2010, the sign consortium is now a well-established stroke genetics network and dataset including over 17,000 ischemic stroke cases recruited from 25 centers in the us and europe. stroke subtyping has been completed on all cases using the web-based causative classification of stroke system, and the cohort contains ~12,000 newly genotyped samples with exome chip data as well as gwas data. isgc platform for accelerating genetic discovery for cerebrovascular disease by generating and analyzing genome-wide genotypes and collecting and analyzing extensive imaging and phenotype data in thousands of individuals with stroke, the isgc has made substantial progress in identifying the genetic variants that influence risk of stroke, the initial step in the discovery cycle. nonetheless, substantial barriers remain to leveraging these and future data for the advancement of our understanding of cerebrovascular disease and the ultimate development of novel therapeutic targets for stroke. datasets are (1) of unprecedented scale, (2) disparate in location, and (3) heterogeneous in type. as a result, the research community lacks the data access and integration necessary in order to perform valid and well-powered comparisons to generate new hypotheses and improve our understanding of cerebrovascular disease biology. dr. rosand has been awarded 1r24ns092983 - 01 to overcome these barriers and inefficiencies in the search for novel therapeutic targets for stroke. in 2017, in partnership with the american heart association’s precision medicine initiative, the isgc launched the cerebrovascular disease knowledge portal , a gateway for data sharing, investigation and analysis. this platform will create a central resource for the investigative community that provides access to summary and individual-level data from disparate datasets contributed by collaborators across the isgc. steering committee members: dr. stephanie debette, bordeaux, france- chair dr. jin-moo lee, st. louis, usa- vice chair dr. daniel woo, cincinnati, usa - immeadiate past chair dr. guido falcone, new haven, usa -junior investigator dr. steven kittner, baltimore, usa dr. jennifer majersik, salt lake city, usa dr. rainer malik, munich, germany dr. agnieszka slowik, krakow, poland dr. matthew traylor, cambridge, united kingdom dr. bradford worrall, charlottesville, usa committees and wo

URL analysis for strokegenetics.com

http://www.strokegenetics.org/user/register
http://www.strokegenetics.org/stroke-information
http://www.strokegenetics.org/node/19
http://www.strokegenetics.org/isgc-publications
http://www.strokegenetics.org/isgc-publications
http://www.strokegenetics.org/user
http://www.strokegenetics.org/participants
http://www.strokegenetics.org/#main-content
http://www.strokegenetics.org/links

Whois Information

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Domain Name: STROKEGENETICS.COM
Domain ID: 1255811909_DOMAIN_COM-VRSN
Registrar WHOIS Server: whois.easydns.com
Registrar URL: http://www.easydns.com
Updated Date: 2016-09-15T13:28:40Z
Creation Date: 2007-10-04T23:34:23Z
Registrar Registration Expiration Date: 2018-10-04T23:34:23Z
Registrar: easyDNS Technologies, Inc.
Registrar IANA ID: 469
Registrar Abuse Contact Email: [email protected]
Registrar Abuse Contact Phone: +1.4165358672
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Registry Registrant ID:
Registrant Name: Lynelle Cortellini
Registrant Organization: Jonathan Rosand- cpzn6818
Registrant Street: CHGR-185 Cambridge S
Registrant City: Boston
Registrant State/Province: MA
Registrant Postal Code: 02114
Registrant Country: US
Registrant Phone: +1.6177242698
Registrant Phone Ext:
Registrant Fax:
Registrant Fax Ext:
Registrant Email: [email protected]
Registry Admin ID:
Admin Name: Lynelle Cortellini
Admin Organization: Jonathan Rosand-CHGR
Admin Street: 185 Cambridge St-- cpzn6818
Admin City: Boston
Admin State/Province: MA
Admin Postal Code: 02114
Admin Country: US
Admin Phone: +1.6177248420
Admin Phone Ext:
Admin Fax:
Admin Fax Ext:
Admin Email: [email protected]
Registry Tech ID:
Tech Name: Lynelle Cortellini
Tech Organization: Jonathan Rosand-CHGR
Tech Street: 185 Cambridge St-- cpzn6818
Tech City: Boston
Tech State/Province: MA
Tech Postal Code: 02114
Tech Country: US
Tech Phone: +1.6177248420
Tech Phone Ext:
Tech Fax:
Tech Fax Ext:
Tech Email: [email protected]
Name Server: NS1.EASYDNS.COM
Name Server: NS2.EASYDNS.COM
Name Server: REMOTE1.EASYDNS.COM
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Name Server: NS3.EASYDNS.ORG
Name Server: NS6.EASYDNS.NET
DNSSEC: unsigned
URL of the ICANN WHOIS Data Problem Reporting System: http://wdprs.internic.net/
>>> Last update of WHOIS database: 2016-09-15T13:28:40Z <<<

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STATUS
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  CHANGED 2016-09-15

  CREATED 2007-10-04

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